A knowledge-based approach to improving effectiveness, quality and risk assessment in the development of solid formulations of drugs, agrochemicals and molecular materials.
In this white paper we introduce a knowledge based approach to improving effectiveness, quality and risk assessment in the development of solid formulations of drugs, agrochemicals and molecular materials
Learn about:
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The cost of failure: we discuss the potential harm that can occur as a result of unaddressed gaps in the understanding of polymorphism in solid form behaviours, especially in late stage development and post product launch, and we review the well-renowned case studies including ritonavir and rotigotine.
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Managing risk: we look at ways to manage these risks and improve reliability of solid state development.
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The Crystal Form Consortium (CFC): we discuss how this forum aims to address the lack of rational design tools for solid form development.
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The 'Health Check' methodology: we explain how a pro-active evaluation of crystal structures of active ingredients is now routine in a number of organisations.
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Benefits of adopting Solid Form Informatics: we look at how it's possible to prevent potential disasters such as that of ritonavir and rotigotine with Solid Form Informatics.